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Psoralenol: the trending anti-aging ingredient?

By | 02/03/2021 08:41

Psoralenol can enhance the activity of human skin fibroblasts, reduce the breakdown of skin collagen, and also promote the synthesis of skin collagen, thus achieving anti-aging effects.

Psoralenol the trending anti-aging ingredient

 

When it comes to the topic of skin aging, we have to mention retinoic acid, which has been hailed as the star of anti-aging.

However, retinoic acid is too irritating, and in order to find raw materials that can replace retinoic acid, A alcohols, A aldehydes, and various A esters and other retinoid-like ingredients have been continuously discovered.

In recent years, there has been more and more research on psoralenol, and its cosmetic and skincare effects have attracted widespread attention, making it a highly promising cosmetic active ingredient with multiple effects.

Psoralen, also known as broken paper, is the mature fruit of the legume Psoralen. The main chemical components of psoralen are coumarins, terpenoids, flavonoids, etc. Psoralenol, also known as broken paper phenol, is one of the main active ingredients of psoralen seeds and belongs to monoterpenes.

Psoralenol is the main component of the volatile oil of psoralen, accounting for about 60%.

Psoralenol is not a vitamin A component, but it is called a functional retinoid component because of its similarity in action to retinol.

 

Psoralea corylifolia Linn.


Anti-aging effects


Psoralenol can enhance the activity of human skin fibroblasts, reduce the breakdown of skin collagen, and also promote the synthesis of skin collagen, thus achieving anti-aging effects.

Of course there is also literature that directly dislikes the operation of this wave of clinical trials, pointing out that retinol is applied 1 time/day while psoralenol is applied 1 time/day/2 times.

 

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In fact, this dislike article from the side to support the irritation of psoralen phenol is lower than retinol, but its anti-aging effect is also slightly inferior to retinol, but the anti-aging disadvantage of psoralen phenol can be improved by increasing the frequency of application.

 

Unlike the effect of retinol on hyperpigmentation, psoralenol mainly affects tyrosine mono- and diphenolase activities. It was found that in the low concentration range, psoralenol inhibits tyrosinase more significantly than arbutin and has the potential to become a natural tyrosinase inhibitor. 

Disclaimer: Echemi reserves the right of final explanation and revision for all the information.

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